Recognizing the Uniqueness of Different Individuals with Schizophrenia
Published:11 Oct.2018    Source:ScienceDaily

 Schizophrenia is an extremely variable psychiatric disorder which is diagnosed based on the presence of specific symptoms. Thomas Wolfers and André Marquand of Radboud university medical center investigated how much the brains of individual patients diagnosed with schizophrenia differ from the 'average' patient. For this purpose, they compared brain scans of 250 healthy individuals with those of 218 individuals with schizophrenia. Those with schizophrenia -- as a group -- differed from the healthy individuals in frontal brain regions, the cerebellum, and the temporal cortex.


However, the differences between individuals were so great that it is virtually meaningless to speak of 'the average patient'. Only a few identical differences in the brain occurred in more than two percent of patients. The largest number of differences were only observed on an individual level. According to Marquand: "The brains of individuals with schizophrenia differ so much from the average that the average has little to say about what might be occurring in the brain of an individual."