Improved Ape Genome Assemblies Provide New Insights into Human Evolution
Published:14 Jun.2018    Source:Science Daily

New, higher-quality assemblies of great ape genomes have now been generated without the guidance of the human reference genome. The effort to reduce "humanizing" discovery bias in great ape genomes provides a clearer view of the genetic differences that arose as humans diverged from other primates.


In the June 8 issue of Science, researchers report on improved orangutan and chimpanzee genomes that were built from scratch using long-read PacBio sequencing and long-range mapping technology. The highly contiguous, newly assembled genomes present a better resource for novel gene discovery and high-resolution comparative genomics amongst the great apes.